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Croda International Plc dspe mpeg
Dspe Mpeg, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 91/100, based on 78 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dspe+peg+2000+amine/DSPE-PEG(2000)+Amine/pm41705321-56-11-12
Average 91 stars, based on 78 article reviews
dspe mpeg - by Bioz Stars, 2026-09
91/100 stars

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Article Title: Colonization of Engineered Bacteria Enhanced Lipid Nanomedicine Accumulation in Tumors for Sonodynamic Immunotherapy,
Article Snippet: DPPC, DSPE-PEG (2000) Amine, and DCcholesterol•HCl were purchased from Avanti Polar Lipids (USA).

Article Title: Toward a Radically Simple Multi-Modal Nasal Spray for Preventing Respiratory Infections.
Article Snippet: Nasal sprays for pre-exposure prophylaxis against respiratory infections show limited protection (20–70%), largely due to their single mechanism of action—either neutralizing pathogens or blocking their entry at the nasal lining, and a failure to maximize the capture of respiratory droplets, allowing them to potentially rebound and reach deeper airways.. This report introduces the Pathogen Capture and Neutralizing Spray (PCANS), which utilizes a multi-modal approach to enhance efficacy.. PCANS coats the nasal cavity, capturing large respiratory droplets from the air, and serving as a physical barrier against a broad spectrum of viruses and bacteria, while rapidly neutralizing them with over 99.99% effectiveness.

Article Title: Carbonic Anhydrase-Inspired Zn-Single-Atom Nanozyme with High Stability for Enhanced CO 2 Hydration Performance.
Article Snippet: Efficient and durable catalysts are essential for enhancing the rate of CO2 hydration in aqueous capture systems and addressing the environmental challenges posed by rising atmospheric CO2 levels.. Traditional capture methods that rely on strongly alkaline solvents face substantial drawbacks, including high regeneration energy costs and safety concerns owing to harmful byproducts.. Carbonic anhydrase (CA), a zinc-containing metalloenzyme, catalyzes CO2 hydration at near-diffusion-limited rates but rapidly degrades in real-world environments.

Article Title: Colonization of engineered bacteria enhanced lipid nanomedicine accumulation in tumors for sonodynamic immunotherapy
Article Snippet: DPPC, DSPE-PEG (2000) Amine, and DC-cholesterol∙HCl were purchased from Avanti Polar Lipids (USA).

Article Title: pH-Responsive Polyethylene Glycol Engagers for Enhanced Brain Delivery of PEGylated Nanomedicine to Treat Glioblastoma
Article Snippet: To prepare amino-PEG-LPs for anti-PEG ELISAs, DiR, DiD and DiO were excluded, and DSPE-mPEG 2000 was replaced by DSPE-PEG 2000 -Amine (Avanti Polar Lipids, Inc.).

Article Title: Codelivery of Raloxifene and Rutin as PEGylated Nanoliposomes: Formulation, Characterization, and Prophylactic Activity Against Breast Cancer
Article Snippet: Hydrogenated soybean phosphatidylcholine (HSPC) lipids, DSPE-PEG (2000) amine, and cholesterol were purchased from Avanti Polar Lipids (Alabama, USA).

Starch:

Article Title: Optimization of Nanoencapsulation of Codium tomentosum Extract and Its Potential Application in Yogurt Fortification
Article Snippet: L-α-phosphatidylcholine (egg yolk, Type XI-E, 100 mg/mL in chloroform, ≥99%, solution), human ApoE3 (recombinant, expressed in E. coli, ≥90% (SDS-PAGE), (HPLC), acetylthiocholine iodide ≥ 98% (TLC), butyrylthiocholine iodide ≥ 98%, butyrylcholinesterase from equine serum, acetylcholinesterase from electric eel, 5,5′-dithiobis(2-nitrobenzoic acid), Trizma® (St. Louis, MO, USA), ≥99.9% (titration), crystalline, bovine serum albumin, cold ethanol fraction, pH 5.2, ≥96%, 1-octanol ACS reagent, suitable for UV/vis spectroscopy, ≥99.5% (GC), 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), disodium fluorescein, potassium phosphate monobasic (KH2PO4), potassium phosphate dibasic trihydrate (K2HPO4·3H2O), and 2′,2′-azobis (2-amidinopropane) dihydrochloride (AAPH) were acquired from Sigma Chemicals Co. (). .. Anhydrous absolute ethanol and 96% sulfuric acid, RPE (for analysis—ISO) were acquired from Carlo Erba Reagents (Chau. du Vexin, Val-de-Reuil, France); ACS BASIC CL0217 chloroform, stabilised with ethanol from Scharlab (Barcelona, Spain), KBr—potassium bromide (IR) PAI and tablets for Kjeldahl (Catalyst with 0.3% CuSO4·5H2O) from Panreac (Darmstadt, Germany); DSPE-PEG(2000) amine (chloroform 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino (polyethylene glycol)—2000]), from Avanti Polar Lipids (Alabaster, AL, USA); soluble starch GR ISO. .. CAS 9005-84-9, pH 6.0–7.5, sodium thiosulfate pentahydrate 99.5% for analysis, both from Merck (Darmstadt, Germany); potassium iodide RPE-ACS, sodium hydroxide AGR, and low metal micro-pearls, from Labbox (Barcelona, Spain); potassium hydrogenophthalate, ≥99.5%, from Honeywell (Charlotte, NC, USA).

Article Title: Optimization of Nanoencapsulation of Codium tomentosum Extract and Its Potential Application in Yogurt Fortification
Article Snippet: L-α-phosphatidylcholine (egg yolk, Type XI-E, 100 mg/mL in chloroform, ≥99%, solution), human ApoE3 (recombinant, expressed in E. coli , ≥90% (SDS-PAGE), (HPLC), acetylthiocholine iodide ≥ 98% (TLC), butyrylthiocholine iodide ≥ 98%, butyrylcholinesterase from equine serum, acetylcholinesterase from electric eel, 5,5′-dithiobis(2-nitrobenzoic acid), Trizma ® (St. Louis, MO, USA), ≥99.9% (titration), crystalline, bovine serum albumin, cold ethanol fraction, pH 5.2, ≥96%, 1-octanol ACS reagent, suitable for UV/vis spectroscopy, ≥99.5% (GC), 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), disodium fluorescein, potassium phosphate monobasic (KH 2 PO 4 ), potassium phosphate dibasic trihydrate (K 2 HPO 4 ·3H 2 O), and 2′,2′-azobis (2-amidinopropane) dihydrochloride (AAPH) were acquired from Sigma Chemicals Co. (). .. Anhydrous absolute ethanol and 96% sulfuric acid, RPE (for analysis—ISO) were acquired from Carlo Erba Reagents (Chau. du Vexin, Val-de-Reuil, France); ACS BASIC CL0217 chloroform, stabilised with ethanol from Scharlab (Barcelona, Spain), KBr—potassium bromide (IR) PAI and tablets for Kjeldahl (Catalyst with 0.3% CuSO 4 ·5H 2 O) from Panreac (Darmstadt, Germany); DSPE-PEG(2000) amine (chloroform 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino (polyethylene glycol)—2000]), from Avanti Polar Lipids (Alabaster, AL, USA); soluble starch GR ISO. .. CAS 9005-84-9, pH 6.0–7.5, sodium thiosulfate pentahydrate 99.5% for analysis, both from Merck (Darmstadt, Germany); potassium iodide RPE-ACS, sodium hydroxide AGR, and low metal micro-pearls, from Labbox (Barcelona, Spain); potassium hydrogenophthalate, ≥99.5%, from Honeywell (Charlotte, NC, USA).



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Synthesis, physicochemical characterization, and pH-responsive release profile of curcin-loaded dual-targeted hybrid solid lipid nanoparticles <t>(HSLNs).</t> (A) Schematic illustration of <t>lipid</t> <t>components-DSPE-PEG(2000)-amine,</t> phosphatidylcholine, and stearic acid- and the thin-film hydration method for generating void and curcin-loaded HSLNs. (B) Conjugation strategy for RGD peptide and TF to create RGD-HSLNs, TF-HSLNs, and Dual (RGD+TF) HSLNs via NHS-EDC chemistry. (C) TEM image showing spherical, monodisperse nanoparticles with vesicular substructures. Scale bar = 200 nm. (D) Hydrodynamic diameter of various HSLN formulations measured by DLS, ranging from 147-192 nm. (E) Zeta potential showing uniformly negative surface charge across all formulations (-20 to -8 mV), with ligand conjugation causing slight surface potential shifts. (F) SDS-PAGE confirming TF conjugation by detection of a ~79 kDa band in TF-HSLNs and Dual-HSLNs. (M: Marker, TF-T: TF-HSLNs, D-T: Dual-HSLNs, T: Transferrin, * represents 75 kDa M.W.) (G) MALDI-TOF mass spectrometry confirming RGD conjugation with a 588.35 m/z peak (arrow), indicative of successful peptide attachment. (H) SDS-PAGE validating curcin encapsulation, showing a 28 kDa band in curcin-loaded HSLNs. (M: Marker, C: Curcin, N-C: Curcin-HSLN, N: Void-HSLN, * represents 25 kDa M.W.). (I) In vitro release profile of curcin from HSLNs under acidic (pH 4.0, 6.5) and physiological (pH 7.4) conditions over 96 h. The biphasic profile includes an initial burst followed by sustained release; significantly higher release was observed under acidic conditions, simulating tumor microenvironments. Data in (D-E, I) are presented as mean ± SD (n = 3 independent replicates). Statistical analysis: one-way ANOVA with Tukey's post hoc test; p < 0.05 (*), p < 0.01 (**).
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Image Search Results


Synthesis, physicochemical characterization, and pH-responsive release profile of curcin-loaded dual-targeted hybrid solid lipid nanoparticles (HSLNs). (A) Schematic illustration of lipid components-DSPE-PEG(2000)-amine, phosphatidylcholine, and stearic acid- and the thin-film hydration method for generating void and curcin-loaded HSLNs. (B) Conjugation strategy for RGD peptide and TF to create RGD-HSLNs, TF-HSLNs, and Dual (RGD+TF) HSLNs via NHS-EDC chemistry. (C) TEM image showing spherical, monodisperse nanoparticles with vesicular substructures. Scale bar = 200 nm. (D) Hydrodynamic diameter of various HSLN formulations measured by DLS, ranging from 147-192 nm. (E) Zeta potential showing uniformly negative surface charge across all formulations (-20 to -8 mV), with ligand conjugation causing slight surface potential shifts. (F) SDS-PAGE confirming TF conjugation by detection of a ~79 kDa band in TF-HSLNs and Dual-HSLNs. (M: Marker, TF-T: TF-HSLNs, D-T: Dual-HSLNs, T: Transferrin, * represents 75 kDa M.W.) (G) MALDI-TOF mass spectrometry confirming RGD conjugation with a 588.35 m/z peak (arrow), indicative of successful peptide attachment. (H) SDS-PAGE validating curcin encapsulation, showing a 28 kDa band in curcin-loaded HSLNs. (M: Marker, C: Curcin, N-C: Curcin-HSLN, N: Void-HSLN, * represents 25 kDa M.W.). (I) In vitro release profile of curcin from HSLNs under acidic (pH 4.0, 6.5) and physiological (pH 7.4) conditions over 96 h. The biphasic profile includes an initial burst followed by sustained release; significantly higher release was observed under acidic conditions, simulating tumor microenvironments. Data in (D-E, I) are presented as mean ± SD (n = 3 independent replicates). Statistical analysis: one-way ANOVA with Tukey's post hoc test; p < 0.05 (*), p < 0.01 (**).

Journal: Theranostics

Article Title: Dual-ligand curcin-loaded hybrid solid lipid nanoparticles achieve durable gliosarcoma remission while preserving neuro-behavioral function

doi: 10.7150/thno.123534

Figure Lengend Snippet: Synthesis, physicochemical characterization, and pH-responsive release profile of curcin-loaded dual-targeted hybrid solid lipid nanoparticles (HSLNs). (A) Schematic illustration of lipid components-DSPE-PEG(2000)-amine, phosphatidylcholine, and stearic acid- and the thin-film hydration method for generating void and curcin-loaded HSLNs. (B) Conjugation strategy for RGD peptide and TF to create RGD-HSLNs, TF-HSLNs, and Dual (RGD+TF) HSLNs via NHS-EDC chemistry. (C) TEM image showing spherical, monodisperse nanoparticles with vesicular substructures. Scale bar = 200 nm. (D) Hydrodynamic diameter of various HSLN formulations measured by DLS, ranging from 147-192 nm. (E) Zeta potential showing uniformly negative surface charge across all formulations (-20 to -8 mV), with ligand conjugation causing slight surface potential shifts. (F) SDS-PAGE confirming TF conjugation by detection of a ~79 kDa band in TF-HSLNs and Dual-HSLNs. (M: Marker, TF-T: TF-HSLNs, D-T: Dual-HSLNs, T: Transferrin, * represents 75 kDa M.W.) (G) MALDI-TOF mass spectrometry confirming RGD conjugation with a 588.35 m/z peak (arrow), indicative of successful peptide attachment. (H) SDS-PAGE validating curcin encapsulation, showing a 28 kDa band in curcin-loaded HSLNs. (M: Marker, C: Curcin, N-C: Curcin-HSLN, N: Void-HSLN, * represents 25 kDa M.W.). (I) In vitro release profile of curcin from HSLNs under acidic (pH 4.0, 6.5) and physiological (pH 7.4) conditions over 96 h. The biphasic profile includes an initial burst followed by sustained release; significantly higher release was observed under acidic conditions, simulating tumor microenvironments. Data in (D-E, I) are presented as mean ± SD (n = 3 independent replicates). Statistical analysis: one-way ANOVA with Tukey's post hoc test; p < 0.05 (*), p < 0.01 (**).

Article Snippet: HSLNs composed of DSPE-PEG(2000) Amine [1,2-distearoyl- sn -glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt) (Avanti Polar Lipids, USA), stearic acid, and lecithin (both from Sigma-Aldrich, USA) were synthesized via a modified lipid co-acervation method .

Techniques: Conjugation Assay, Zeta Potential Analyzer, SDS Page, Marker, Mass Spectrometry, Encapsulation, In Vitro

Synthesis, physicochemical characterization, and pH-responsive release profile of curcin-loaded dual-targeted hybrid solid lipid nanoparticles (HSLNs). (A) Schematic illustration of lipid components-DSPE-PEG(2000)-amine, phosphatidylcholine, and stearic acid- and the thin-film hydration method for generating void and curcin-loaded HSLNs. (B) Conjugation strategy for RGD peptide and TF to create RGD-HSLNs, TF-HSLNs, and Dual (RGD+TF) HSLNs via NHS-EDC chemistry. (C) TEM image showing spherical, monodisperse nanoparticles with vesicular substructures. Scale bar = 200 nm. (D) Hydrodynamic diameter of various HSLN formulations measured by DLS, ranging from 147-192 nm. (E) Zeta potential showing uniformly negative surface charge across all formulations (-20 to -8 mV), with ligand conjugation causing slight surface potential shifts. (F) SDS-PAGE confirming TF conjugation by detection of a ~79 kDa band in TF-HSLNs and Dual-HSLNs. (M: Marker, TF-T: TF-HSLNs, D-T: Dual-HSLNs, T: Transferrin, * represents 75 kDa M.W.) (G) MALDI-TOF mass spectrometry confirming RGD conjugation with a 588.35 m/z peak (arrow), indicative of successful peptide attachment. (H) SDS-PAGE validating curcin encapsulation, showing a 28 kDa band in curcin-loaded HSLNs. (M: Marker, C: Curcin, N-C: Curcin-HSLN, N: Void-HSLN, * represents 25 kDa M.W.). (I) In vitro release profile of curcin from HSLNs under acidic (pH 4.0, 6.5) and physiological (pH 7.4) conditions over 96 h. The biphasic profile includes an initial burst followed by sustained release; significantly higher release was observed under acidic conditions, simulating tumor microenvironments. Data in (D-E, I) are presented as mean ± SD (n = 3 independent replicates). Statistical analysis: one-way ANOVA with Tukey's post hoc test; p < 0.05 (*), p < 0.01 (**).

Journal: Theranostics

Article Title: Dual-ligand curcin-loaded hybrid solid lipid nanoparticles achieve durable gliosarcoma remission while preserving neuro-behavioral function

doi: 10.7150/thno.123534

Figure Lengend Snippet: Synthesis, physicochemical characterization, and pH-responsive release profile of curcin-loaded dual-targeted hybrid solid lipid nanoparticles (HSLNs). (A) Schematic illustration of lipid components-DSPE-PEG(2000)-amine, phosphatidylcholine, and stearic acid- and the thin-film hydration method for generating void and curcin-loaded HSLNs. (B) Conjugation strategy for RGD peptide and TF to create RGD-HSLNs, TF-HSLNs, and Dual (RGD+TF) HSLNs via NHS-EDC chemistry. (C) TEM image showing spherical, monodisperse nanoparticles with vesicular substructures. Scale bar = 200 nm. (D) Hydrodynamic diameter of various HSLN formulations measured by DLS, ranging from 147-192 nm. (E) Zeta potential showing uniformly negative surface charge across all formulations (-20 to -8 mV), with ligand conjugation causing slight surface potential shifts. (F) SDS-PAGE confirming TF conjugation by detection of a ~79 kDa band in TF-HSLNs and Dual-HSLNs. (M: Marker, TF-T: TF-HSLNs, D-T: Dual-HSLNs, T: Transferrin, * represents 75 kDa M.W.) (G) MALDI-TOF mass spectrometry confirming RGD conjugation with a 588.35 m/z peak (arrow), indicative of successful peptide attachment. (H) SDS-PAGE validating curcin encapsulation, showing a 28 kDa band in curcin-loaded HSLNs. (M: Marker, C: Curcin, N-C: Curcin-HSLN, N: Void-HSLN, * represents 25 kDa M.W.). (I) In vitro release profile of curcin from HSLNs under acidic (pH 4.0, 6.5) and physiological (pH 7.4) conditions over 96 h. The biphasic profile includes an initial burst followed by sustained release; significantly higher release was observed under acidic conditions, simulating tumor microenvironments. Data in (D-E, I) are presented as mean ± SD (n = 3 independent replicates). Statistical analysis: one-way ANOVA with Tukey's post hoc test; p < 0.05 (*), p < 0.01 (**).

Article Snippet: HSLNs composed of DSPE-PEG(2000) Amine [1,2-distearoyl- sn -glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt) (Avanti Polar Lipids, USA), stearic acid, and lecithin (both from Sigma-Aldrich, USA) were synthesized via a modified lipid co-acervation method .

Techniques: Conjugation Assay, Zeta Potential Analyzer, SDS Page, Marker, Mass Spectrometry, Encapsulation, In Vitro